A case report on intermediate-grade malignant meningeal melanocytoma with elevated cell proliferation index.
نویسندگان
چکیده
Meningeal melanocytoma is a kind of extremely rare pigmented tumor of the central nervous system, which often occurs in the groove around the base of the brain and spinal pia mater. Age of onset is 40 to 50 years old, mostly presenting a benign course of disease and the prognosis is good. Case reports of partial invasion or metastasis from lesions are even rarer. This report described a case of 56-year-old meningeal melanoma patient with partial skull and muscle invasion at the lantooccipital transition zone. Intraoperative histological examination showed moderate malignancy and Ki-67 index was 10%.
منابع مشابه
Malignant transformation of intramedullary melanocytoma: case report.
OBJECTIVE Meningeal melanocytomas are low-grade primary melanocytic tumors with benign histological features and a favorable clinical prognosis. Transition from meningeal melanocytoma to primary melanoma of the central nervous system is exceptionally rare, with only 5 cases having been previously reported. Here, we discuss a case of malignant transformation of an intramedullary melanocytoma to ...
متن کاملSpinal Meningeal Melanocytoma with Benign Histology Showing Leptomeningeal Spread: Case Report
Meningeal melanocytoma is a rare benign tumor with relatively good prognosis. However, local aggressive behavior of meningeal melanocytoma has been reported, especially in cases of incomplete surgical resection. Malignant transformation was raised as possible cause by prior reports to explain this phenomenon. We present an unusual case of meningeal melanocytoma associated with histologically be...
متن کاملIntracranial Meningeal Melanocytoma: Review of the Literature
Primary pigmented tumors of the cerebrospinal meninges are rare and uncommon group of melanin-containing neoplasms. They include pigmented meningioma, malignant melanoma, meningeal melanocytoma, melanotic schwannoma and melanoblastosis. These tumors are different in biological behavior, treatment and prognosis. Valenti was the first to describe pigmented cells normally found in the leptomeninge...
متن کاملCervical Spinal Meningeal Melanocytoma Presenting as Intracranial Superficial Siderosis
Meningeal melanocytoma is a rare pigmented tumor of the leptomeningeal melanocytes. This rare entity results in diagnostic difficulty in imaging unless clinical and histopathology correlation is performed. In this case report, we describe a case of meningeal melanocytoma of the cervical region presenting with superficial siderosis. Extensive neuroradiological examination is necessary to locate ...
متن کاملProgressive visual and hearing loss as looming manifestations of spinal meningeal melanocytoma
The term "meningeal melanocytoma" was first used by Limas and Tio in 1972 to describe a benign tumor of melanocytic origin arising from the leptomeninges [2]. In the World Health Organization classification of brain tumor, meningeal melanocytoma represents a subgroup of primary melanocytic lesion, which most frequently originates from the leptomeninges of posterior fossa or along the spinal cor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- International journal of clinical and experimental pathology
دوره 8 9 شماره
صفحات -
تاریخ انتشار 2015